Page 164 - The Vasculitides, Volume 1: General Considerations and Systemic Vasculitis

140 J. Charles Jennette, Ronald J. Falk and Adil. H. M. Gasim

Figure 12. Necrotizing arteritis in the perirenal adipose tissue of a patient with systemic lupus
erythematosus showing focal fibrinoid necrosis and leukocyte infiltration (H a& E stain).

Vasculitis Associated with Probable Etiology

CHCC 2012 acknowledges that vasculitis may be associated with a probable specific
etiology [1]. In this case, the name or diagnosis should have a prefix term specifying the
association, for example hydralazine-associated microscopic polyangiitis, HBV-associated
vasculitis and HCV-associated CV, minocycline-associated vasculitis, and paraneoplastic
vasculitis.

In so much as categorization refers to an association with a system disease, its relation to
etiology requires subjective decisions about terminological hierarchy with some etiologic
relationships reflected in the names of major categories and others designated in categorical
subsets. For example, propylthiouracil-associated MPO-ANCA and HCV-associated CV are
designations that each refer to two different etiologies that act in sequence to cause vasculitis,
highlighting the importance of using diagnostic terms that provide information about likely or
definite causes of vasculitis in a given patient.

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