Page 89 - The Vasculitides, Volume 1: General Considerations and Systemic Vasculitis
P. 89
In: The Vasculitides, Volume 1 ISBN: 978-1-63463-110-5
Editors: David S. Younger © 2015 Nova Science Publishers, Inc.
Chapter 3
Epidemiology of Primary
Systemic Vasculitis
David S. Younger, M.D., M.P.H. ?
Department of Neurology, New York University
School of Medicine; and the Global Institute of Public Health**,
New York University, New York, NY, US
Abstract
The epidemiology of vasculitis has witnessed extraordinary advances in the past
decade influenced by the worldwide increased recognition and accurate classification and
diagnosis of the vasculitides, and insights brought by genome-wide association studies
and other genetic investigations that contribute to the understanding of the heritable
factors of some of the disorders. This chapter reviews the current knowledge of the
epidemiology of vasculitides in different global regions.
Keywords: Global, Burden, Vasculitis
Introduction
The publication of recent genome-wide association studies has brought awareness to the
understanding of susceptibility factors and designated genetic risk loci for many of the
vasculitides supporting the interplay of immunologic, environmental, and shared genetic
susceptibility in the etiopathogenesis of these disorders. They show a very complex etiology
? Corresponding author: David S. Younger, M.D., M.P.H., 333 East 34th Street, 1J, New York, NY 10016.
Email: [email protected].
** The author is a Master of Public Health degree candidate in the Global Institute of Public Health (GIPH) of New
York University, New York; and a Master of Science degree candidate in Epidemiology at the Mailman School
of Public Health, Columbia University, New York.
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