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Information for families of children with PANDAS

Families of children with PANDAS will be interested to know that this disorder is a likely product of the interactions of the human microbiome and infection. In keeping with the dynamic relation of infection, immunity and inflammation contained in I-Cubed, illness arises when protective immunity becomes the source of autoimmunity, conditioned by environmental and genetic factors. Treatment employing immune-modulatory therapy may be beneficial especially in children with evidence of underlying immune deficiencies or altered immunity.